![]() ![]() ![]() ![]() 47 To the extent that these findings generalize to humans, this could help explain the increased vulnerability for addiction to other substances of misuse later in life that most epidemiological studies have reported for people who begin marijuana use early in life. 46 Marijuana use is also linked to other substance use disorders including nicotine addiction.Įarly exposure to cannabinoids in adolescent rodents decreases the reactivity of brain dopamine reward centers later in adulthood. For instance, a study using longitudinal data from the National Epidemiological Study of Alcohol Use and Related Disorders found that adults who reported marijuana use during the first wave of the survey were more likely than adults who did not use marijuana to develop an alcohol use disorder within 3 years people who used marijuana and already had an alcohol use disorder at the outset were at greater risk of their alcohol use disorder worsening. Some research suggests that marijuana use is likely to precede use of other licit and illicit substances 45 and the development of addiction to other substances. ![]()
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